Do you know yourHER2 status?
Hear about HER2
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so, what exactly
is her2?
first, let’s talk
about biomarkers
HER2 is a type of biomarker. Biomarkers can show us whether processes in the cell are working the way they should. And they can help doctors understand how metastatic non-small cell lung cancer may progress and how it might respond to treatment.
Normally, HER2 is a protein that helps
cells grow and repair themselves.
But too much HER2 may cause
cells to grow uncontrollably and
become cancerous.
Mutations in the HER2 gene can also
cause abnormal cell
activity and
promote
the uncontrolled growth of cells.
Normally, HER2 is a protein that helps cells grow and repair themselves.
But too much HER2 may cause cells to grow uncontrollably and become cancerous.
Mutations in the HER2 gene can also cause abnormal cell activity and promote the uncontrolled growth of cells.
The amount of HER2 on the surface of cancer cells can also help to determine someone's HER2 status.
HER2 matters in
METASTATIC NON-SMALL
CELL lung cancer
HER2 matters in
METASTATIC NON-SMALL
CELL lung cancer
High levels of HER2 protein, or a mutation in the HER2 gene, can be linked to more aggressive cancers. That’s why knowing your HER2 status is important. It may change the way your cancer is treated.
It's unusual, but high levels of HER2 or a HER2 mutation may be found in people with metastatic non-small cell lung cancer.
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do you know
your her2 status?
To figure out your HER2 status, your doctor might use one or both of these two tests.
-
One, called immunohistochemistry (IHC), looks at how much
HER2 protein is on the surface of the cancer cells.
-
The
other, next-generation
sequencing (NGS), looks at the DNA to see if there are
changes in the HER2 gene.
Both give your doctor helpful information about the characteristics of your cancer.
Ask to get tested.
Your doctor can perform a biopsy, which takes a small sample of your tumor to see if you’re HER2-positive or have a mutation in your HER2 gene if you have metastatic non-small cell lung cancer. If you’ve already had one, you can ask your doctor to reexamine a sample from an existing biopsy. If you haven’t had a biopsy, your doctor can perform one to confirm your HER2 status.
Okay, what happens next?
If the test shows that you’re HER2-positive, your doctor may recommend a targeted treatment plan that’s fine-tuned to your cancer.
If you have metastatic non-small cell lung cancer and your test shows that you have a mutation in your HER2 gene, your doctor may also recommend a targeted treatment plan that's fine-tuned to your cancer.
Ask for another look at your biopsy.
Even if you’ve been tested before, there might be more to your HER2 status than you previously thought.
Ask your doctor to reexamine your biopsy results to ensure that you know your HER2 status is up-to-date.
Don’t let the conversation slip your mind. Talking to your doctor about your HER2 status may help shape personalized care.
now you know your
her2 status matters
and so do your
options
Discover how your HER2 status may change your METASTATIC NON-SMALL CELL LUNG CANCER plan
Not an actual patient.
Hear About HER2
Learn why others
believe HER2 status
matters
Dr hatim husain, a medical oncologist specializing in non-small cell lung cancer, discusses why HER2 status matters
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METASTATIC NON-SMALL
CELL LUNG CANCER
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